Hamzeh spent the last decade investing in global digital health companies. He was most recently an Investment Director at Debiopharm Innovation Fund, the Corporate Venture Capital (CVC) arm of Debiopharm International; a Pharmaceutical drug developer company based in Switzerland. Prior to that he worked at Hikma Ventures; the Corporate Venture Capital arm of Hikma Pharmaceuticals for 6 years and was involved in closing 17 Global Digital Health deals. He served as a Board Observer for Lemonaid Health, Click Therapeutics, WinterLight Labs Inc., and SeamlessMD. He was also a board member with Genialis, Inc., Fosanis (Mika), Altis Labs, and Whitelab Genomics.

In the 2015, Hamzeh was part of the corporate treasury team at Hikma Pharmaceuticals PLC (LON:HIK).

He previously held various finance roles at Phillips Morris International and Capital Investments.

After graduating from the George Washington University in 2010 with a Bachelor of Business Administration majoring in Finance, Hamzeh helped organize TedxDeadSea in Jordan. He was also the founder of a social networking platform based in Madrid, Spain.